Reconsidering the Use of Minocycline in the Preliminary Treatment Regime of Rheumatoid Arthritis
Identifieur interne : 004000 ( Main/Exploration ); précédent : 003F99; suivant : 004001Reconsidering the Use of Minocycline in the Preliminary Treatment Regime of Rheumatoid Arthritis
Auteurs :Source :
- Cureus [ 2168-8184 ] ; ????.
Abstract
Strong epidemiologic, clinical, and basic science studies have identified a number of factors that may lead to rheumatoid arthritis (RA) onset and progression, particularly involving the complex interplay between genomics, environmental risk factors, the breakdown of immune self-tolerance, and microbiome dysbiosis. A chronic state of inflammation established by infectious agents has long been suspected to set the stage for the development of RA. The purpose of this article is to review the contribution of the gut, lung, and oral microbiomes to the pathogenesis of RA and consider the importance of supplementing the preliminary treatment regime of RA patients with antibiotics, in particular, minocycline. Minocycline has been used in the treatment of RA due to its bacteriostatic, as well as immunomodulatory and anti-inflammatory properties. Ultimately, a short course of antibiotic treatment with minocycline may eliminate pathogenic organisms contributing to the development and progression of RA.
Url:
DOI: 10.7759/cureus.5351
PubMed: 31608186
PubMed Central: 6783212
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000939
- to stream Pmc, to step Curation: 000939
- to stream Pmc, to step Checkpoint: 000B09
- to stream Ncbi, to step Merge: 000A98
- to stream Ncbi, to step Curation: 000A98
- to stream Ncbi, to step Checkpoint: 000A98
- to stream Main, to step Merge: 004088
- to stream Main, to step Curation: 004000
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Reconsidering the Use of Minocycline in the Preliminary Treatment Regime of Rheumatoid Arthritis</title></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">31608186</idno><idno type="pmc">6783212</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783212</idno><idno type="RBID">PMC:6783212</idno><idno type="doi">10.7759/cureus.5351</idno><date when="????">????</date><idno type="wicri:Area/Pmc/Corpus">000939</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000939</idno><idno type="wicri:Area/Pmc/Curation">000939</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000939</idno><idno type="wicri:Area/Pmc/Checkpoint">000B09</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000B09</idno><idno type="wicri:Area/Ncbi/Merge">000A98</idno><idno type="wicri:Area/Ncbi/Curation">000A98</idno><idno type="wicri:Area/Ncbi/Checkpoint">000A98</idno><idno type="wicri:Area/Main/Merge">004088</idno><idno type="wicri:Area/Main/Curation">004000</idno><idno type="wicri:Area/Main/Exploration">004000</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Reconsidering the Use of Minocycline in the Preliminary Treatment Regime of Rheumatoid Arthritis</title></analytic><series><title level="j">Cureus</title><idno type="eISSN">2168-8184</idno><imprint><date when="????">????</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Strong epidemiologic, clinical, and basic science studies have identified a number of factors that may lead to rheumatoid arthritis (RA) onset and progression, particularly involving the complex interplay between genomics, environmental risk factors, the breakdown of immune self-tolerance, and microbiome dysbiosis. A chronic state of inflammation established by infectious agents has long been suspected to set the stage for the development of RA. The purpose of this article is to review the contribution of the gut, lung, and oral microbiomes to the pathogenesis of RA and consider the importance of supplementing the preliminary treatment regime of RA patients with antibiotics, in particular, minocycline. Minocycline has been used in the treatment of RA due to its bacteriostatic, as well as immunomodulatory and anti-inflammatory properties. Ultimately, a short course of antibiotic treatment with minocycline may eliminate pathogenic organisms contributing to the development and progression of RA. </p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Firestein, Gs" uniqKey="Firestein G">GS Firestein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hunter, Tm" uniqKey="Hunter T">TM Hunter</name></author><author><name sortKey="Boytsov, Nn" uniqKey="Boytsov N">NN Boytsov</name></author><author><name sortKey="Zhang, X" uniqKey="Zhang X">X Zhang</name></author><author><name sortKey="Schroeder, K" uniqKey="Schroeder K">K Schroeder</name></author><author><name sortKey="Michaud, K" uniqKey="Michaud K">K Michaud</name></author><author><name sortKey="Araujo, Ab" uniqKey="Araujo A">AB Araujo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Turesson, C" uniqKey="Turesson C">C Turesson</name></author><author><name sortKey="O Fallon, Wm" uniqKey="O Fallon W">WM O'Fallon</name></author><author><name sortKey="Crowson, Cs" uniqKey="Crowson C">CS Crowson</name></author><author><name sortKey="Gabriel, Se" uniqKey="Gabriel S">SE Gabriel</name></author><author><name sortKey="Matteson, El" uniqKey="Matteson E">EL Matteson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Der Woude, D" uniqKey="Van Der Woude D">D van der Woude</name></author><author><name sortKey="Alemayehu, Wg" uniqKey="Alemayehu W">WG Alemayehu</name></author><author><name sortKey="Verduijn, W" uniqKey="Verduijn W">W Verduijn</name></author><author><name sortKey="De Vries, Rr" uniqKey="De Vries R">RR de Vries</name></author><author><name sortKey="Houwing Duistermaat, Jj" uniqKey="Houwing Duistermaat J">JJ Houwing-Duistermaat</name></author><author><name sortKey="Huizinga, Tw" uniqKey="Huizinga T">TW Huizinga</name></author><author><name sortKey="Toes, Re" uniqKey="Toes R">RE Toes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Horta Baas, G" uniqKey="Horta Baas G">G Horta-Baas</name></author><author><name sortKey="Romero Figueroa, Mds" uniqKey="Romero Figueroa M">MDS Romero-Figueroa</name></author><author><name sortKey="Montiel Jarquin, Aj" uniqKey="Montiel Jarquin A">AJ Montiel-Jarquín</name></author><author><name sortKey="Pizano Zarate, Ml" uniqKey="Pizano Zarate M">ML Pizano-Zárate</name></author><author><name sortKey="Garcia Mena, J" uniqKey="Garcia Mena J">J García-Mena</name></author><author><name sortKey="Ramirez Duran, N" uniqKey="Ramirez Duran N">N Ramírez-Durán</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lourido, L" uniqKey="Lourido L">L Lourido</name></author><author><name sortKey="Blanco, Fj" uniqKey="Blanco F">FJ Blanco</name></author><author><name sortKey="Ruiz Romero, C" uniqKey="Ruiz Romero C">C Ruiz-Romero</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scher, Ju" uniqKey="Scher J">JU Scher</name></author><author><name sortKey="Joshua, V" uniqKey="Joshua V">V Joshua</name></author><author><name sortKey="Artacho, A" uniqKey="Artacho A">A Artacho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bennike, Tb" uniqKey="Bennike T">TB Bennike</name></author><author><name sortKey="Ellingsen, T" uniqKey="Ellingsen T">T Ellingsen</name></author><author><name sortKey="Glerup, H" uniqKey="Glerup H">H Glerup</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scher, Ju" uniqKey="Scher J">JU Scher</name></author><author><name sortKey="Sczesnak, A" uniqKey="Sczesnak A">A Sczesnak</name></author><author><name sortKey="Longman, Rs" uniqKey="Longman R">RS Longman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scher, Ju" uniqKey="Scher J">JU Scher</name></author><author><name sortKey="Ubeda, C" uniqKey="Ubeda C">C Ubeda</name></author><author><name sortKey="Equinda, M" uniqKey="Equinda M">M Equinda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mikuls, Tr" uniqKey="Mikuls T">TR Mikuls</name></author><author><name sortKey="Payne, Jb" uniqKey="Payne J">JB Payne</name></author><author><name sortKey="Reinhardt, Ra" uniqKey="Reinhardt R">RA Reinhardt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Smit, M" uniqKey="De Smit M">M de Smit</name></author><author><name sortKey="Westra, J" uniqKey="Westra J">J Westra</name></author><author><name sortKey="Vissink, A" uniqKey="Vissink A">A Vissink</name></author><author><name sortKey="Doornbos Van Der Meer, B" uniqKey="Doornbos Van Der Meer B">B Doornbos-van der Meer</name></author><author><name sortKey="Brouwer, E" uniqKey="Brouwer E">E Brouwer</name></author><author><name sortKey="Van Winkelhoff, Aj" uniqKey="Van Winkelhoff A">AJ van Winkelhoff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheng, Z" uniqKey="Cheng Z">Z Cheng</name></author><author><name sortKey="Meade, J" uniqKey="Meade J">J Meade</name></author><author><name sortKey="Mankia, K" uniqKey="Mankia K">K Mankia</name></author><author><name sortKey="Emery, P" uniqKey="Emery P">P Emery</name></author><author><name sortKey="Devine, Da" uniqKey="Devine D">DA Devine</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scher, Ju" uniqKey="Scher J">JU Scher</name></author><author><name sortKey="Abramson, Sb" uniqKey="Abramson S">SB Abramson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cruz, Fm" uniqKey="Cruz F">FM Cruz</name></author><author><name sortKey="Colbert, Jd" uniqKey="Colbert J">JD Colbert</name></author><author><name sortKey="Merino, E" uniqKey="Merino E">E Merino</name></author><author><name sortKey="Kriegsman, Ba" uniqKey="Kriegsman B">BA Kriegsman</name></author><author><name sortKey="Rock, Kl" uniqKey="Rock K">KL Rock</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yu, Hc" uniqKey="Yu H">HC Yu</name></author><author><name sortKey="Lu, Mc" uniqKey="Lu M">MC Lu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schellekens, Ga" uniqKey="Schellekens G">GA Schellekens</name></author><author><name sortKey="Visser, H" uniqKey="Visser H">H Visser</name></author><author><name sortKey="De Jong, Ba" uniqKey="De Jong B">BA de Jong</name></author><author><name sortKey="Van Den Hoogen, Fh" uniqKey="Van Den Hoogen F">FH van den Hoogen</name></author><author><name sortKey="Hazes, Jm" uniqKey="Hazes J">JM Hazes</name></author><author><name sortKey="Breedveld, Fc" uniqKey="Breedveld F">FC Breedveld</name></author><author><name sortKey="Van Venrooij, Wj" uniqKey="Van Venrooij W">WJ van Venrooij</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Torow, N" uniqKey="Torow N">N Torow</name></author><author><name sortKey="Marsland, Bj" uniqKey="Marsland B">BJ Marsland</name></author><author><name sortKey="Hornef, Mw" uniqKey="Hornef M">MW Hornef</name></author><author><name sortKey="Gollwitzer, Es" uniqKey="Gollwitzer E">ES Gollwitzer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Den Broek, Mf" uniqKey="Van Den Broek M">MF van den Broek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lehman, Tj" uniqKey="Lehman T">TJ Lehman</name></author><author><name sortKey="Allen, Jb" uniqKey="Allen J">JB Allen</name></author><author><name sortKey="Plotz, Ph" uniqKey="Plotz P">PH Plotz</name></author><author><name sortKey="Wilder, Rl" uniqKey="Wilder R">RL Wilder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, Hj" uniqKey="Wu H">HJ Wu</name></author><author><name sortKey="Ivanov, Ii" uniqKey="Ivanov I">II Ivanov</name></author><author><name sortKey="Darce, J" uniqKey="Darce J">J Darce</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Maeda, Y" uniqKey="Maeda Y">Y Maeda</name></author><author><name sortKey="Kurakawa, T" uniqKey="Kurakawa T">T Kurakawa</name></author><author><name sortKey="Umemoto, E" uniqKey="Umemoto E">E Umemoto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Costenbader, Kh" uniqKey="Costenbader K">KH Costenbader</name></author><author><name sortKey="Karlson, Ew" uniqKey="Karlson E">EW Karlson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcgraw, Wt" uniqKey="Mcgraw W">WT McGraw</name></author><author><name sortKey="Potempa, J" uniqKey="Potempa J">J Potempa</name></author><author><name sortKey="Farley, D" uniqKey="Farley D">D Farley</name></author><author><name sortKey="Travis, J" uniqKey="Travis J">J Travis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Konig, Mf" uniqKey="Konig M">MF Konig</name></author><author><name sortKey="Abusleme, L" uniqKey="Abusleme L">L Abusleme</name></author><author><name sortKey="Reinholdt, J" uniqKey="Reinholdt J">J Reinholdt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chhibber Goel, J" uniqKey="Chhibber Goel J">J Chhibber-Goel</name></author><author><name sortKey="Singhal, V" uniqKey="Singhal V">V Singhal</name></author><author><name sortKey="Bhowmik, D" uniqKey="Bhowmik D">D Bhowmik</name></author><author><name sortKey="Vivek, R" uniqKey="Vivek R">R Vivek</name></author><author><name sortKey="Parakh, N" uniqKey="Parakh N">N Parakh</name></author><author><name sortKey="Bhargava, B" uniqKey="Bhargava B">B Bhargava</name></author><author><name sortKey="Sharma, A" uniqKey="Sharma A">A Sharma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Song, S" uniqKey="Song S">S Song</name></author><author><name sortKey="Yu, Y" uniqKey="Yu Y">Y Yu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chopra, I" uniqKey="Chopra I">I Chopra</name></author><author><name sortKey="Roberts, M" uniqKey="Roberts M">M Roberts</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Agwuh, Kn" uniqKey="Agwuh K">KN Agwuh</name></author><author><name sortKey="Macgowan, A" uniqKey="Macgowan A">A MacGowan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pruzanski, W" uniqKey="Pruzanski W">W Pruzanski</name></author><author><name sortKey="Greenwald, Ra" uniqKey="Greenwald R">RA Greenwald</name></author><author><name sortKey="Street, Lp" uniqKey="Street L">LP Street</name></author><author><name sortKey="Laliberte, F" uniqKey="Laliberte F">F Laliberte</name></author><author><name sortKey="Stefanski, E" uniqKey="Stefanski E">E Stefanski</name></author><author><name sortKey="Vadas, P" uniqKey="Vadas P">P Vadas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Greenwald, Ra" uniqKey="Greenwald R">RA Greenwald</name></author><author><name sortKey="Moak, Sa" uniqKey="Moak S">SA Moak</name></author><author><name sortKey="Ramamurthy, Ns" uniqKey="Ramamurthy N">NS Ramamurthy</name></author><author><name sortKey="Golub, Lm" uniqKey="Golub L">LM Golub</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wasil, M" uniqKey="Wasil M">M Wasil</name></author><author><name sortKey="Halliwell, B" uniqKey="Halliwell B">B Halliwell</name></author><author><name sortKey="Moorhouse, Cp" uniqKey="Moorhouse C">CP Moorhouse</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kloppenburg, M" uniqKey="Kloppenburg M">M Kloppenburg</name></author><author><name sortKey="Breedveld, Fc" uniqKey="Breedveld F">FC Breedveld</name></author><author><name sortKey="Terwiel, Jp" uniqKey="Terwiel J">JP Terwiel</name></author><author><name sortKey="Mallee, C" uniqKey="Mallee C">C Mallee</name></author><author><name sortKey="Dijkmans, Ba" uniqKey="Dijkmans B">BA Dijkmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tilley, Bc" uniqKey="Tilley B">BC Tilley</name></author><author><name sortKey="Alarc N, Gs" uniqKey="Alarc N G">GS Alarcón</name></author><author><name sortKey="Heyse, Sp" uniqKey="Heyse S">SP Heyse</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="O Dell, Jr" uniqKey="O Dell J">JR O'Dell</name></author><author><name sortKey="Haire, Ce" uniqKey="Haire C">CE Haire</name></author><author><name sortKey="Palmer, W" uniqKey="Palmer W">W Palmer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="O Dell, Jr" uniqKey="O Dell J">JR O'Dell</name></author><author><name sortKey="Blakely, Kw" uniqKey="Blakely K">KW Blakely</name></author><author><name sortKey="Mallek, Ja" uniqKey="Mallek J">JA Mallek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Langevitz, P" uniqKey="Langevitz P">P Langevitz</name></author><author><name sortKey="Bank, I" uniqKey="Bank I">I Bank</name></author><author><name sortKey="Zemer, D" uniqKey="Zemer D">D Zemer</name></author><author><name sortKey="Book, M" uniqKey="Book M">M Book</name></author><author><name sortKey="Pras, M" uniqKey="Pras M">M Pras</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Breedveld, Fc" uniqKey="Breedveld F">FC Breedveld</name></author><author><name sortKey="Dijkmans, Ba" uniqKey="Dijkmans B">BA Dijkmans</name></author><author><name sortKey="Mattie, H" uniqKey="Mattie H">H Mattie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Skinner, M" uniqKey="Skinner M">M Skinner</name></author><author><name sortKey="Cathcart, Es" uniqKey="Cathcart E">ES Cathcart</name></author><author><name sortKey="Mills, Ja" uniqKey="Mills J">JA Mills</name></author><author><name sortKey="Pinals, Rs" uniqKey="Pinals R">RS Pinals</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Der Laan, W" uniqKey="Van Der Laan W">W van der Laan</name></author><author><name sortKey="Molenaar, E" uniqKey="Molenaar E">E Molenaar</name></author><author><name sortKey="Ronday, K" uniqKey="Ronday K">K Ronday</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pillemer, S" uniqKey="Pillemer S">S Pillemer</name></author><author><name sortKey="Gulko, P" uniqKey="Gulko P">P Gulko</name></author><author><name sortKey="Ligier, S" uniqKey="Ligier S">S Ligier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="St Clair, Ew" uniqKey="St Clair E">EW St. Clair</name></author><author><name sortKey="Wilkinson, We" uniqKey="Wilkinson W">WE Wilkinson</name></author><author><name sortKey="Pisetsky, Ds" uniqKey="Pisetsky D">DS Pisetsky</name></author><author><name sortKey="Sexton, Dj" uniqKey="Sexton D">DJ Sexton</name></author><author><name sortKey="Drew, R" uniqKey="Drew R">R Drew</name></author><author><name sortKey="Kraus, Vb" uniqKey="Kraus V">VB Kraus</name></author><author><name sortKey="Greenwald, Ra" uniqKey="Greenwald R">RA Greenwald</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stone, M" uniqKey="Stone M">M Stone</name></author><author><name sortKey="Fortin, Pr" uniqKey="Fortin P">PR Fortin</name></author><author><name sortKey="Pacheco Tena, C" uniqKey="Pacheco Tena C">C Pacheco-Tena</name></author><author><name sortKey="Inman, Rd" uniqKey="Inman R">RD Inman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mukherjee, A" uniqKey="Mukherjee A">A Mukherjee</name></author><author><name sortKey="Jantsch, V" uniqKey="Jantsch V">V Jantsch</name></author><author><name sortKey="Khan, R" uniqKey="Khan R">R Khan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oettinger Barak, O" uniqKey="Oettinger Barak O">O Oettinger-Barak</name></author><author><name sortKey="Dashper, Sg" uniqKey="Dashper S">SG Dashper</name></author><author><name sortKey="Catmull, Dv" uniqKey="Catmull D">DV Catmull</name></author><author><name sortKey="Adams, Gg" uniqKey="Adams G">GG Adams</name></author><author><name sortKey="Sela, Mn" uniqKey="Sela M">MN Sela</name></author><author><name sortKey="Machtei, Ee" uniqKey="Machtei E">EE Machtei</name></author><author><name sortKey="Reynolds, Ec" uniqKey="Reynolds E">EC Reynolds</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smith, Cj" uniqKey="Smith C">CJ Smith</name></author><author><name sortKey="Sayles, H" uniqKey="Sayles H">H Sayles</name></author><author><name sortKey="Mikuls, Tr" uniqKey="Mikuls T">TR Mikuls</name></author><author><name sortKey="Michaud, K" uniqKey="Michaud K">K Michaud</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Elkayam, O" uniqKey="Elkayam O">O Elkayam</name></author><author><name sortKey="Yaron, M" uniqKey="Yaron M">M Yaron</name></author><author><name sortKey="Caspi, D" uniqKey="Caspi D">D Caspi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tariq, R" uniqKey="Tariq R">R Tariq</name></author><author><name sortKey="Cho, J" uniqKey="Cho J">J Cho</name></author><author><name sortKey="Kapoor, S" uniqKey="Kapoor S">S Kapoor</name></author><author><name sortKey="Orenstein, R" uniqKey="Orenstein R">R Orenstein</name></author><author><name sortKey="Singh, S" uniqKey="Singh S">S Singh</name></author><author><name sortKey="Pardi, Ds" uniqKey="Pardi D">DS Pardi</name></author><author><name sortKey="Khanna, S" uniqKey="Khanna S">S Khanna</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Friedman, Gd" uniqKey="Friedman G">GD Friedman</name></author><author><name sortKey="Oestreicher, N" uniqKey="Oestreicher N">N Oestreicher</name></author><author><name sortKey="Chan, J" uniqKey="Chan J">J Chan</name></author><author><name sortKey="Quesenberry Cp, Jr" uniqKey="Quesenberry Cp J">Jr Quesenberry CP</name></author><author><name sortKey="Udaltsova, N" uniqKey="Udaltsova N">N Udaltsova</name></author><author><name sortKey="Habel, La" uniqKey="Habel L">LA Habel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boursi, B" uniqKey="Boursi B">B Boursi</name></author><author><name sortKey="Mamtani, R" uniqKey="Mamtani R">R Mamtani</name></author><author><name sortKey="Haynes, K" uniqKey="Haynes K">K Haynes</name></author><author><name sortKey="Yang, Yx" uniqKey="Yang Y">YX Yang</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004000 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004000 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:6783212
|texte= Reconsidering the Use of Minocycline in the Preliminary Treatment Regime of Rheumatoid Arthritis
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:31608186" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a ChloroquineV1
| This area was generated with Dilib version V0.6.33. |  |